ABSTRACT
Methanol extracts of whole body (Melampus ceylonicus), blood (Anadara rhombea) and hepatopancreas (Sepiella inermis) were screened for antifungal and cytotoxic activity. Blood of A. rhombea and hepatopancreas of S. inermis strongly inhibited Candida albicans, Mucor racemosus and Penicillium expansum. A. rhombea appear to exert strong cytotoxic activity against vertebrate erythrocytes. The bacterial pathogens (Escherichia coli and Vibrio cholarae) were not inhibited by any of the three tested methanol extracts.
Subject(s)
Animals , Antifungal Agents/pharmacology , Antineoplastic Agents/pharmacology , Methanol/chemistry , Microbial Sensitivity Tests , Mollusca , Species SpecificityABSTRACT
Aqueous extracts of ink from four cephalopods, adult and young Sepiella inermis and Loligo duvaucelli were tested against Moloney murine leukaemia virus reverse transcriptase (MMLV RT). Ink from young cephalopods, S. intermis and L. duvaucelli showed strong inhibition of MMLV RT.